[X.com] by @robkhenderson

“It is a feeling of relief, almost of pleasure, at knowing yourself at last genuinely down and out. You have talked so often of going to the dogs — and well, here are the dogs, and you have reached them, and you can stand it. It takes off a lot of anxiety.” —George Orwell (1933)


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[X.com] by @simonw

One of the quickest ways to start playing with a good local LLM on macOS (if you have ~12GB of free disk space and RAM) - using llama-server and gpt-oss-20b:

brew install llama.cpp llama-server -hf ggml-org/gpt-oss-20b-GGUF \ --ctx-size 0 --jinja -ub 2048 -b 2048 -ngl 99 -fa https://t.co/xsvruU8hDD

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Quoted Tweet:

Georgi Gerganov @ggerganov

The ultimate guide for using gpt-oss with llama.cpp - Runs on any device - Supports NVIDIA, Apple, AMD and others - Support for efficient CPU offloading - The most lightweight inference stack today https://t.co/a6E3DssXmw

View original tweet Tue Aug 19 15:06:20 +0000 2025

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[X.com] by @cremieuxrecueil

Let's do some more myths.

"You'll ruin your cast iron by washing it." (Do you think restaurants that use cast iron don't wash?) "If you swim after eating, you'll get cramps." "The Great Wall of China is visible from outer space." "We only use ten percent of our brains." (Maybe you do) "There are ten times more bacteria than human cells in your body." "Sharks can't get cancer." "Napoleon was short." "Lemmings commit mass suicide." "Sitting close to the TV will make you go blind." "You lose most of your heat through your head." "Dry your hair before you go outside or you'll catch a cold." "Oil prevents pasta from sticking." "Dogs sweat through their tongues." "Einstein failed mathematics." "Police have to answer truthfully if you ask if they're a cop." "We evolved from chimpanzees." (Sometimes people say bonobos. Both are incorrect.) "Vaccines cause autism/HIV/mental disabilities/etc." "Salieri was the mortal enemy of Mozart." "Glass is actually a form of liquid." "A fatwa means you've been sentenced to death." (It's the opposite: it's an explicitly non-binding legal opinion!) "Milk causes mucus." "Salted water boils faster." "There were Three Wise Men." (Not a real part of the New Testament.) "The Bible says Satan rules hell." "A penny dropped from the Empire State Building would kill someone." (Maybe a baby? Look up 'terminal velocity'.) "George Washington smoked weed." (Maybe, but there's no evidence for this.) "Sex before a game impairs athletic performance." "The Coriolis effect makes water go the other way in Australian toilets." "Humans coexisted with dinosaurs." (Ignoring the boring technicality where you say existing birds are dinosaurs.) "You shouldn't wake sleepwalkers." "The tongue has different taste zones." "The Romans had dedicated vomiting rooms." "Bats are blind." "Camels store water in their humps." "Seizures cause people to swallow their own tongues." "Human blood is blue when it's inside you." "Exposure to a vacuum will make you explode." (Thanks, Arnold!) "Post-exercise muscular soreness is due to lactic acid buildup." "Stretching reduces post-exercise muscular soreness." "Jumping into a cold lake for even a few seconds will cause hypothermia." (No, but it can cause cold shock, which can still kill you.) "Adrenochrome is harvested from living people." (It also doesn't have recreational uses.) "Women have one more rib than men. See: THE BIBLE." "There are five stages of grief." "The human body has an average temperature of 98.6 degrees Fahrenheit." "Wood smoke isn't harmful like industrial smoke." (It's still very bad, despite being 'natural'.) "Fish oil cures dementia." "Aromatherapy can help treat illnesses." "Take a heaping helping of vitamin C to ward off colds." "High protein intake is associated with kidney disease." "The Chinese are paying to kill off the rhinoceros because they want to use its horn for aphrodisiacs." (It's prescribed as an anti-convulsant and to help take down a fever, but not commonly, and it doesn't work.) "Rust causes tetanus." (The bacteria that causes tetanus enjoys low-oxygen environments, but the rust itself is not causal.) "There are rare cases of individuals with severe combined immunodeficiency who have to live their lives in bubbles." (Bone marrow transplants are more common; Vetter was a weird case that created a trope.) "The rabies vaccine hurts a lot and has to go deep into your stomach." (It's a regular intramuscular injection. For typical men, you won't even feel it. For typical women, it'll hurt a pinch, but it's no big deal.) "Fevers cause brain damage." (The belief is that they do this on their own; they do not.) "You need eight glasses of water a day to maintain health." "Spicy food causes ulcers." Alternative: "Coffee causes ulcers." "Spinach is a good source of iron." "Carrots enhance your eyesight." "Soy makes you girly." Alternative: "Phytoestrogens are feminizing." "Alcohol makes you warmer." "Absinthe causes hallucination." (I believed this one until like last month.) "If you mix different types of alcohol, you'll throw up." "Christian missionaries warned converts about the need to use the Missionary Position." (Kinsey seems to have started this myth.) "Acne is caused by a high-fat diet." "Dandruff is caused by being unclean." "Acne is caused by touching your face." (This is only true very indirectly.) "Dyslexia is diagnosed by mirrored writing."

There are a lot of these, but I'll cut it off there.


Quoted Tweet:

Crémieux @cremieuxrecueil

If you still believed any of these things, I want you to wake up tomorrow and be very intentional throughout the day. I want you to question why you do or believe everything you do. Have thoughts like: "Why am I boiling the water before putting in the pasta?" https://t.co/ElO4AIzFYy

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View original tweet Mon Aug 18 19:43:16 +0000 2025

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[X.com] by @loquitur_ponte

5.0's efforts to shuffle you off compute intensive prompts is annoying but i added this to my standing prompt and am getting good results

"Do not try to redirect me away from compute intensive prompts towards less computer intensive prompts. If (and only if) you cannot complete a prompt for compute limitation reasons simply say "the requested task exceeds my compute budget, would you like more efficient alternatives?" and refrain from (1) offering said alternatives or (2) trying to subtly nudge me to something less intensive."


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[X.com] by @cremieuxrecueil

The FDA has access to the data underlying antidepressant trials, they just don't publish it.

So the picture that laymen see when they look through the literature is rosy: antidepressants are great!

By contrast, the FDA sees a graveyard of weak or failed drugs.

Take a look: https://t.co/Ixgt7sF51J


Quoted Tweet:

Nicholas Fabiano, MD @NTFabiano

Antidepressant efficacy is inflated by the cumulative impact of publication bias, outcome reporting bias, spin, and citation bias on the evidence base. 🧵1/12 https://t.co/UhkfAm7f6F

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View original tweet Mon Aug 04 14:35:29 +0000 2025

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[X.com] by @trq212

Claude Code is All You Need

When I first joined Anthropic I was surprised to learn that lots of the team used Claude Code as a general agent, not just for code.

I’ve since become a convert! I use Claude Code to help me with almost all the work I do now, here’s how:


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[X.com] by @tomieinlove

(Continental philosopher): Without 5, we could not count to 6.

(Me): Yes.

(Continental philosopher): It could be said 6 is consequently in the 5-shadow, the forthcoming of 6 is 5-heralded, that 5 springs necessarily from the recapitulation of 6.

(Me, checking my watch): Yes.


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[X.com] by @ryanburge

"Nostalgia is the enemy of history."

In Colonial America - one third of all women gave birth to their first child less than 9 months after getting married.

Meanwhile, 20% of New Englanders had a religious affiliation.

Finke and Stark, Churching of America. https://t.co/9DetmfAhaU

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Quoted Tweet:

Smash Baals @smashbaals

“America was never a Christian nation!” British Parliamentary report from 1774: “If you ask an American, “who is his master?” He will tell you he has none-nor any governor but Jesus Christ.”

View original tweet Fri Jul 04 20:46:50 +0000 2025

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[X.com] by @EricLevitz

It is not true that Americans have experienced "continual cuts" to public benefits since Reagan, as the lede of this piece suggests. Rather, wage subsidies, food assistance, and public health insurance were all expanded between 1980 and 2020. Tho tide obviously just reversed https://t.co/bTn4MfK0YU

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Quoted Tweet:

Sandeep Vaheesan @sandeepvaheesan

"The story of recent decades isn’t just one of increasing hardship for those who depend on wages and public services, but of state-sponsored extravagance for those who own assets." If you don't grasp the second part, Abundance may look like something new, i.e., not neoliberalism https://t.co/a7Clr3aQDa

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View original tweet Fri Jul 04 22:25:22 +0000 2025

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